国产白白视-国产白浆视频-国产白浆在线观看-国产白领-国产白嫩初高中生被c-国产白拍-国产白丝jk被疯狂输-国产白丝喷

資料下載

Data download

當前位置:首頁資料下載上海騰拔質(zhì)構(gòu)儀用于微針力學強度測試

上海騰拔質(zhì)構(gòu)儀用于微針力學強度測試

發(fā)布時間:2023/8/7點擊次數(shù):1643

Abstract: Silicon microneedle (Si-MN) systems are a promising strategy for transdermal drug delivery due to their minimal invasiveness and ease of processing and application. Traditional Si-MN arrays are usually fabricated by using micro-electro-mechanical system (MEMS) processes, which are expensive and not suitable for large-scale manufacturing and applications. In addition, Si-MNs have a smooth surface, making it difficult for them to achieve high-dose drug delivery. Herein, we

demonstrate a solid strategy to prepare a novel black silicon microneedle (BSi-MN) patch with ultrahydrophilic surfaces for high drug loading. The proposed strategy consists of a simple fabrication of plain Si-MNs and a subsequent fabrication of black silicon nanowires. First, plain Si-MNs were prepared via a simple method consisting of laser patterning and alkaline etching. The nanowire structures were then prepared on the surfaces of the plain Si-MNs to form the BSi-MNs through Ag-catalyzed chemical etching. The effects of preparation parameters, including Ag+ and HF concentrations during Ag nanoparticle deposition and [HF/(HF + H2O2)] ratio during Ag-catalyzed chemical etching, on the morphology and properties of the BSi-MNs were investigated in detail. The results show that the final prepared BSi-MN patches exhibit an excellent drug loading capability, more than twice that of plain Si-MN patches with the same area, while maintaining comparable mechanical properties for practical skin piercing applications. Moreover, the BSi-MNs exhibit a certain antimicrobial activity that is expected to prevent bacterial growth and disinfect the affected area when applied to the skin.



文件下載    
服務(wù)熱線

021-54397372

15618141270

15300622190

添加微信

返回頂部





主站蜘蛛池模板: 自慰高潮网站在线观看 | 中文字幕亚洲无码在线 | 日韩国产校园综合 | 成人午夜免费无码区老司机视频 | 欧美又黄又大又爽a片三年片 | 99久久国产精品免费热日韩 | 国产精品美女久久久久久久 | 手机版免费av在线 | 美女扒开腿让男人桶视频在线观看 | 丁香五月天色婷婷 | 国产丝袜第| 无遮挡粉嫩小泬久久久久 | 中文日产幕无线码系列 | 在线观看亚洲AV无码每日更新 | 国产高清自产拍av | 亚洲av成人一区国产精品 | 国产午夜福利精品视频 | 国产精品欧美v片免费观看 国产精品欧美福利 | 成人生活片网站 | 精品国产丝袜自在线拍国语 | 国产一区二区三区婷婷五月 | 国产精品av毛片免费观看网站 | 国产精品成人扳**a毛片 | 国产1女3男4p精品久久 | 成人特黄午夜性a一级毛片 成人特级毛片 | 日韩av无码中文无码不卡电影 | 91久久国产口精品久久久 | 亚洲欧洲日韩另类自拍 | 91成人午夜精品福利院在线观看 | 一级毛片一级毛片一级毛片一级毛片 | 国产成人精品日本亚洲专区 | 久久99国产亚洲精品观看 | 69久久国产露脸精品国产 | 日本午夜视频在线观看 | 亚洲欧美视频手机在线 | 999中文字幕在线视频观看 | 一本道婷婷久久欧美 | 国产日韩美国成人 | 国产精品秘一区二区三区高潮 | 精品国产9999一区二区三区 | 国产一区二区四区在线观看 |